Health Benefits

Three Principals Strategies To Improve The Ratio Of Good to Bad Bacteria

Three-in-one approach to gut health

P.UF1™ has benefits on all three crucial strategies

  • Propionibacterium freudenreichii UF1 (P.UF1™)
    High resistance to acids and bile salts, survival within the digestive tract,
    and metabolic activity in the colon
  • Propionibacterium freudenreichii UF1 (P.UF1™)
    P.UF1™ stimulates the growth of beneficial bacteria with bifidogeneic
  • Propionibacterium freudenreichii UF1 (P.UF1™)
    protects organism against growth of pathogenic microorganisms by
    generating bacteriocins

Postbiotic: micronutrients produced by a probiotic bacteria having a beneficial effect on health

Propionibacterium freudenreichii UF1 (P.UF1™) significantly produces

  • Vitamin B12, B2, B5, C, K, Biotin, Folic Acid
  • Short-Chain Fatty Acids: propionate, acetate
  • Amino Acids: Tyrosine, Phenylalanine, Tryptophan

Propionibacteria excrete

  • lipases (enzymes that breakdown fats (e.g., lipids). The
    lipolytic activity of propionibacteria is about 100-fold higher
    than that of lactic acid bacteria (LAB))
  • proteases (enzymes that breakdown protein). The proteolytic
    activity of propionibacteria is low compared to LAB.
  • bacteriocins (peptides with antimicrobial activity)
Main metabolic pathways of propionibacteria.

Reference: C. Deborde, PROPIONIBACTERIUM spp., ed. H. Roginski, Encyclopedia of Dairy Sciences, Elsevier, 2002, 2330-2339.

Regulatory status

Propionibacterium freudenreichii is listed on the Qualified presumption of safety (QPS) list.

Propionibacterium freudenreichii is GRAS.
Propionibacterium freudenreichii UF1 self-affirmed GRAS pending.

Propionibacterium freudenreichii UF1 NPN application pending.